{"id":555,"date":"2021-04-26T15:10:23","date_gmt":"2021-04-26T12:10:23","guid":{"rendered":"https:\/\/www.silmasaatio.fi\/levinnyt-suonikalvoston-melanooma\/"},"modified":"2024-11-22T11:43:24","modified_gmt":"2024-11-22T09:43:24","slug":"utbrett-uvealt-melanom","status":"publish","type":"post","link":"https:\/\/www.silmasaatio.fi\/sv\/utbrett-uvealt-melanom\/","title":{"rendered":"Utbrett uvealt melanom"},"content":{"rendered":"

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Forskandet av \u00f6goncancer \u00e4r samarbete bland specialistl\u00e4kare inom olika medicinska omr\u00e5den.<\/em><\/p>\n

Uvealt melanom \u00e4r den vanligaste formen av \u00f6gonmelanom hos vuxna. I de nordiska l\u00e4nderna \u00e4r incidensen h\u00f6gst i v\u00e4rlden. Patientantalet \u00f6kar d\u00e5 Finlands befolkning \u00e5ldras och uvealt melanom blir vanligare i takt med \u00e5ldern.<\/p>\n

Modertum\u00f6ren kan i dagsl\u00e4get behandlas effektivt \u2013 \u00e5terfall sker bara hos 5\u201310 procent av patienterna. Tum\u00f6rcellerna sprider sig dock i ett tidigt skede, redan innan modertum\u00f6ren uppt\u00e4cks. H\u00e4lften av patienterna d\u00f6r till f\u00f6ljd av metastaser inom 25 \u00e5r. Tum\u00f6ren sprids prim\u00e4rt via blodet till levern, men metastaser kan \u00e4ven finnas bland annat i lungorna, skelettet, huden och lymfk\u00f6rtlarna. Metastaser uppkommer vanligtvis 2\u20135 \u00e5r efter att modertum\u00f6ren uppt\u00e4ckts.<\/p>\n<\/div>\n<\/div>\n

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Screening och behandling av metastaser<\/h2>\n

Det f\u00f6rekommer inte samf\u00f6rst\u00e5nd g\u00e4llande screening och behandling av metastaser. F\u00f6r min avhandling samlade jag in uppgifter om 338 patienter ur det nationella materialet. Dessa patienters modertum\u00f6rer behandlades p\u00e5 \u00f6gonkliniken p\u00e5 HUCS och utbrett melanom hos dessa patienter konstaterades mellan \u00e5r 1999 och 2016.<\/p>\n

\u201dMina resultat fr\u00e4mjar ibruktagande av den b\u00e4sta screenings- och behandlingsv\u00e4gen och f\u00f6rb\u00e4ttrar v\u00e5rdunders\u00f6kningarnas j\u00e4mf\u00f6rbarhet\u201d.<\/p>\n

F\u00f6rst klargjorde jag hur resultaten fr\u00e5n ultraljudsunders\u00f6kningen, datortomografin och magnetr\u00f6ntgen st\u00e4mde \u00f6verens sinsemellan i samband med screeningen av metastaser. Ultraljudsunders\u00f6kningen var k\u00e4nslig att uppt\u00e4cka metastaser, och man kommer att forts\u00e4tta anv\u00e4nda ultraljudsunders\u00f6kning som en nationell screeningsmetod.<\/p>\n

D\u00e4refter delade jag upp patienterna enligt behandlingsform i grupper, och j\u00e4mf\u00f6rde f\u00f6rv\u00e4ntad livstid med prognosfaktorer s\u00e5som \u00e5lder, allm\u00e4nkondition och metastasernas storlek. Livstiden i medeltal vid utbredd \u00f6gontum\u00f6r efter att den konstaterats var 13 m\u00e5nader. Endast kirurgiska ingrepp f\u00f6rl\u00e4ngde tydligt livstiden, men endast i samband med vissa best\u00e4mda prognosfaktorer. En operation var m\u00f6jlig bara n\u00e4r sjukdomen var lokal, det vill s\u00e4ga f\u00f6r patienternas del, mycket s\u00e4llan.<\/p>\n

F\u00f6r tillf\u00e4llet fokuserar jag i min forskning i synnerhet p\u00e5 de patienter som efter att de f\u00e5tt sin diagnos levde l\u00e4ngre \u00e4n f\u00f6rv\u00e4ntat.<\/p>\n

Forskningsarbete inom \u00f6gonsjukdomar<\/h2>\n

Silm\u00e4s\u00e4\u00e4ti\u00f6s beviljade stipendium betydde mycket f\u00f6r mig f\u00f6r att f\u00e5 min avhandling f\u00e4rdig. N\u00e4r en forskare f\u00e5r ett stipendium ska \u00e4rmarna kavlas upp och arbetet p\u00e5b\u00f6rjas. Forskningsarbetet best\u00e5r \u00e4ven av frustrerande stunder d\u00e5 projektet inte framskrider p\u00e5 f\u00f6rv\u00e4ntat s\u00e4tt. \u00d6gontum\u00f6r som forskningsobjekt tycker jag \u00e4r meningsfullt. Syftet \u00e4r att prognosen f\u00f6r patienter med \u00f6gontum\u00f6r f\u00f6rb\u00e4ttras. Forskning \u00e4r samarbete Samarbetet sker mellan patienter, l\u00e4kare, sjukhus och specialiteter, s\u00e5v\u00e4l i Finland som internationellt. En \u00f6ppen forskning fr\u00e4mjar samarbetet mellan forskarna samt forskningsr\u00f6nens transparens och tillg\u00e4nglighet. Vid sidan av \u00f6ppenhet ska dataskyddet och etiska principer ovillkorligen beaktas.<\/p>\n

\u201dF\u00f6rutom att Silm\u00e4s\u00e4\u00e4ti\u00f6s beviljade stipendium har gjort mitt forskningsarbete m\u00f6jligt har det \u00e4ven gett mig en skyldighet\u201d.<\/p>\n

Jag \u00e4r tacksam f\u00f6r f\u00f6rtroendet och hoppas att stiftelsen \u00e4ven i framtiden har m\u00f6jlighet att st\u00f6dja forskningsarbete inom min specialitet.<\/p>\n

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Artikelf\u00f6rfattaren\u00a0Elina Rantala<\/strong>\u00a0\u00e4r medicine doktor, FEBO, specialistl\u00e4kare i \u00f6gonsjukdomar och har specialkompetens\u00a0inom \u00f6gonkirurgi\u00a0<\/strong>och arbetar som forskare vid Helsingfors universitet. Doktor Rantala har beviljats ett ett\u00e5rigt stipendium\u00a0<\/em>av Silm\u00e4s\u00e4\u00e4ti\u00f6<\/em><\/a>.\u00a0<\/em><\/p>\n

Artikelns bild Lightspring\/Schutterstock.com<\/em><\/p>\n<\/section>\n","protected":false},"excerpt":{"rendered":"

Forskandet av \u00f6goncancer \u00e4r samarbete bland specialistl\u00e4kare inom olika medicinska omr\u00e5den. Uvealt melanom \u00e4r den vanligaste formen av \u00f6gonmelanom hos vuxna. I de nordiska l\u00e4nderna…<\/p>\n","protected":false},"author":1,"featured_media":305,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-555","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aktuell"],"yoast_head":"\nUtbrett uvealt melanom - Silm\u00e4s\u00e4\u00e4ti\u00f6<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.silmasaatio.fi\/sv\/utbrett-uvealt-melanom\/\" \/>\n<meta property=\"og:locale\" content=\"sv_SE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Utbrett uvealt melanom - Silm\u00e4s\u00e4\u00e4ti\u00f6\" \/>\n<meta property=\"og:description\" content=\"Forskandet av \u00f6goncancer \u00e4r samarbete bland specialistl\u00e4kare inom olika medicinska omr\u00e5den. 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